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I was working on one crm org, and today when I tried to log back into system and tried accessing the page, I was getting following error screen.

 After spending bit of time. Following is the resolution I have applied.
Click on Setting icon and go to internet option

Go to 'Connections' tab and click on 'LAN settings' button

On the 'Local Area Network (LAN) Settings' make sure 'Automatically detect settings is checked and the option 'Use a proxy server for your LAN (These settings will not apply to dial-up or VPN connections)' should be un-checked.